Scientometrics
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 16, 2021; 9(11): 2503-2518
Published online Apr 16, 2021. doi: 10.12998/wjcc.v9.i11.2503
Prognostic nomograms for predicting overall survival and cause-specific survival of signet ring cell carcinoma in colorectal cancer patients
Fu-Rong Kou, Yang-Zi Zhang, Wei-Ran Xu
Fu-Rong Kou, Department of Day Oncology Unit, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital and Institute, Beijing 100142, China
Yang-Zi Zhang, Department of Radiation Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital and Institute, Beijing 100142, China
Wei-Ran Xu, Department of Oncology, Peking University International Hospital, Beijing 102206, China
Author contributions: Kou FR contributed to research design, data collection, interpretation, and analysis, and manuscript drafting; Zhang YZ contributed to data collection, interpretation, and analysis; Xu WR contributed to study design, data analysis, result interpretation, and critical revision of the manuscript; all authors approved the final version and agree to be accountable for all aspects of the work.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest to disclose.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei-Ran Xu, MD, Doctor, Department of Oncology, Peking University International Hospital, Life Science Park of Zhongguancun, Changping District, Beijing 102206, China. xiaoyao444444@126.com
Received: December 7, 2020
Peer-review started: December 7, 2020
First decision: January 25, 2021
Revised: January 28, 2021
Accepted: February 11, 2021
Article in press: February 11, 2021
Published online: April 16, 2021
Core Tip

Core Tip: Using data from the Surveillance, Epidemiology, and End Results database between 2004 and 2015, convenient and visual nomograms were built and validated to accurately predict 1-, 3-, and 5-year overall survival and cause-specific survival rates for signet ring cell carcinoma in colorectal cancer patients for the first time. The novel nomograms stratified patients into high-risk, moderate-risk, and low-risk groups with 5-year probability survival of 6.8%, 37.7%, and 67.0% for overall survival (P < 0.001), as well as 9.6%, 38.5%, and 67.6% for cause-specific survival (P < 0.001), respectively. Besides, these nomograms were proved to be superior to the conventional tumor-node-metastasis staging system.