Iguratimod promotes transformation of mononuclear macrophages in elderly patients with rheumatoid arthritis by nuclear factor-κB pathway
Sha Liu, Li-Ping Song, Rong-Bin Li, Le-Heng Feng, Hui Zhu, Department of Rheumatism, The First Hospital of Qiqihar, Affiliated Qiqihar Hospital of Southern Medical University, Qiqihar 161005, Heilongjiang Province, China
Author contributions: All authors participated in the writing and final approval of the manuscript; Liu S, Zhu H, Song LP, and Li RB contributed to the conception and design of the study; Zhu H, Song LP, Li RB, and Feng LH performed the data collection and summarization; Liu S, Zhu H, Song LP, and Li RB performed the data analysis and interpretation.
Institutional review board statement: The study was reviewed and approved by the Medical Ethics Committee of Qiqihar First Hospital.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: The authors give informed consent to data sharing.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
http://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Hui Zhu, MPhil, Associate Chief Physician, Department of Rheumatism, The First Hospital of Qiqihar, Affiliated Qiqihar Hospital of Southern Medical University, No. 30 Gongyuan Road, Longsha District, Qiqihar 161005, Heilongjiang Province, China.
zhuhui0223@163.com
Received: December 11, 2020
Peer-review started: December 11, 2020
First decision: December 30, 2020
Revised: January 13, 2021
Accepted: February 11, 2021
Article in press: February 11, 2021
Published online: April 6, 2021
Processing time: 108 Days and 23 Hours