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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 6, 2021; 9(1): 91-101
Published online Jan 6, 2021. doi: 10.12998/wjcc.v9.i1.91
Published online Jan 6, 2021. doi: 10.12998/wjcc.v9.i1.91
Role of relaxin in diastasis of the pubic symphysis peripartum
Yan Wang, Rehabilitation Medicine, Taian City Central Hospital, Taian 271000, Shandong Province, China
Yong-Qiang Li, Department of Otolaryngology, Taian City Central Hospital, Taian 271000, Shandong Province, China
Mei-Rong Tian, Department of Obstetrics, Taian City Central Hospital, Taian 271000, Shandong Province, China
Nan Wang, Rehabilitation Centre, Qingdao Fuwai Cardiovascular Hospital, Qingdao 266034, Shandong Province, China
Zun-Cheng Zheng, Department of Rehabilitation, Taian City Central Hospital, Taian 271000, Shandong Province, China
Author contributions: Zheng ZC designed the study, supervised the study performance, and revised the manuscript; Wang Y developed the project and participated in the acquisition, analysis, and interpretation of the data; Li YQ, Tian MR and Wang N analyzed the data, drafted the manuscript, and critically revised the manuscript for intellectual content.
Supported by The Science and Technology Development Plan of Taian , No. 2018NS0203 .
Institutional review board statement: The study protocol was reviewed and approved by the Ethics Committee of Taian City Central Hospital.
Informed consent statement: All study participants, or their legal guardians, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zun-Cheng Zheng, MAMS, Chief Doctor, Director, Professor, Department of Rehabilitation, Taian City Central Hospital, No. 29 Longtan Road, Taian 271000, Shandong Province, China. zhengzc1965@126.com
Received: June 15, 2020
Peer-review started: June 15, 2020
First decision: September 13, 2020
Revised: October 10, 2020
Accepted: November 13, 2020
Article in press: November 13, 2020
Published online: January 6, 2021
Peer-review started: June 15, 2020
First decision: September 13, 2020
Revised: October 10, 2020
Accepted: November 13, 2020
Article in press: November 13, 2020
Published online: January 6, 2021
Core Tip
Core Tip: Peripartum separation of the pubic symphysis is not a frequent pregnancy complication, but it can cause chronic pelvic pain and difficult ambulation. Furthermore, it limits activities of daily living (ADL). We performed a cross-sectional study and identified an association between postpartum serum relaxin (RLX) levels and neonatal weight with peripartum separation of the pubic symphysis. The degree of separation of the pubic symphysis was positively correlated with the degree of pain and was negatively correlated with ADL. Serum RLX levels and neonatal weight may be used to identify women at a high risk of pubic symphysis separation peripartum.