Removal of biofilm is essential for long-term ventilation tube retention
Qiang Ma, Hui Wang, Zheng-Nong Chen, Ya-Qin Wu, Dong-Zhen Yu, Peng-Jun Wang, Hai-Bo Shi, Kai-Ming Su
Qiang Ma, Hui Wang, Zheng-Nong Chen, Ya-Qin Wu, Dong-Zhen Yu, Peng-Jun Wang, Hai-Bo Shi, Kai-Ming Su, Department of Otorhinolaryngology–Head & Neck Surgery, the Sixth People’s Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, China
Hai-Bo Shi, Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai 200233, China
Author contributions: Ma Q wrote the manuscript draft; Wang PJ and Shi HB collected the clinical data; Shi HB designed the study; Wang PJ revised the manuscript; Chen ZN, Wu YQ, and Wang H performed the treatments; Su KM and Yu DZ evaluated the efficacy of the method; all authors read and approved the final manuscript.
Supported by Shanghai Leadership Talent Training Plan, No. 2017062; the Key Project of Shanghai Jiao Tong University Medicine Science and Engineering Interdisciplinary Foundation, No. YG2016ZD02; Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support, No. 20152233; Multi-Center Clinical Research Plan of Medical College of Shanghai Jiao Tong University, No. DLY201823; the Clinical Research Plan of Shanghai Shen Kang Hospital Development Center, No. 16CR4022A and No. 16CR3041A; and National Natural Science Foundation of China, No. 81974142.
Institutional review board statement: The study was approved by the Ethics Committee of Shanghai Sixth People’s Hospital (YS-2018-101).
Informed consent statement: All patients gave informed consent.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement, and the manuscript was prepared and revised according to the STROBE Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Peng-Jun Wang, MD, Doctor, Department of Otorhinolaryngology-Head & Neck Surgery, the Sixth People's Hospital Affiliated to Shanghai Jiaotong University, 600 Yishan Road, Shanghai 200233, China. wangpj@sjtu.edu.cn
Received: December 16, 2019
Peer-review started: December 16, 2019
First decision: February 20, 2020
Revised: March 4, 2020
Accepted: April 15, 2020
Article in press: April 15, 2020
Published online: May 6, 2020
