Lakananurak N, Gramlich L. Nutrition management in acute pancreatitis: Clinical practice consideration. World J Clin Cases 2020; 8(9): 1561-1573 [PMID: 32432134 DOI: 10.12998/wjcc.v8.i9.1561]
Corresponding Author of This Article
Narisorn Lakananurak, MD, MSc, Doctor, Department of Medicine, Faculty of Medicine, Chulalongkorn University, 254 Phayathai Road, Pathumwan, Bangkok 10330, Thailand. narisorn.l@chula.ac.th
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. May 6, 2020; 8(9): 1561-1573 Published online May 6, 2020. doi: 10.12998/wjcc.v8.i9.1561
Nutrition management in acute pancreatitis: Clinical practice consideration
Narisorn Lakananurak, Leah Gramlich
Narisorn Lakananurak, Leah Gramlich, Department of Medicine, University of Alberta, Edmonton T6G 2R3, Alberta, Canada
Narisorn Lakananurak, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand
Author contributions: All authors equally contributed to this paper with conception and design of the study, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.
Conflict-of-interest statement: No potential conflicts of interest. No financial support.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Narisorn Lakananurak, MD, MSc, Doctor, Department of Medicine, Faculty of Medicine, Chulalongkorn University, 254 Phayathai Road, Pathumwan, Bangkok 10330, Thailand. narisorn.l@chula.ac.th
Received: December 20, 2019 Peer-review started: December 20, 2019 First decision: January 12, 2020 Revised: March 7, 2020 Accepted: April 21, 2020 Article in press: April 21, 2020 Published online: May 6, 2020 Processing time: 131 Days and 16.6 Hours
Core Tip
Core tip: Nutrition intervention helps prevent malnutrition and is a key to reduce inflammation, complications, and death in acute pancreatitis. Current evidence supports the benefits of early enteral nutrition in severe pancreatitis. Gastric and jejunal feeding are equally effective, and polymeric formula is safe, compared to peptide-based formula. Parenteral nutrition should be considered in patients who cannot tolerate enteral nutrition. According to recent data, nutritional supplements, including glutamine, probiotics, omega-3 fatty acids, and antioxidants, may contribute to positive outcomes. While intravenous glutamine shows promising benefits in patients receiving total parenteral nutrition, further studies in other nutritional supplements are needed.
