Copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 6, 2020; 8(7): 1213-1222
Published online Apr 6, 2020. doi: 10.12998/wjcc.v8.i7.1213
Published online Apr 6, 2020. doi: 10.12998/wjcc.v8.i7.1213
Clinical significance and prognostic value of tumor necrosis factor-α and dickkopf related protein-1 in ankylosing spondylitis
Jun-Hui Xiong, Jian Liu, Jian Chen, Department of Rheumatology, Lishui People’s Hospital, Lishui 323000, Zhejiang Province, China
Author contributions: Xiong JH contributed to the study design and reviewed the manuscript; Liu J analyzed the data and contributed to manuscript writing; Xiong JH and Chen J contributed to data collection, data interpretation and manuscript writing; All authors read and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Lishui People’s Hospital Ethics Committee.
Informed consent statement: All patients in our study provided informed consent.
Conflict-of-interest statement: The authors declare no conflict of interest.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Jian Chen, BSc, Attending Doctor, Department of Rheumatology, Lishui People’s Hospital, No. 15 Dazhong Street, Liandu District, Lishui 323000, Zhejiang Province, China. cairuke99@163.com
Received: December 25, 2019
Peer-review started: December 25, 2019
First decision: February 20, 2020
Revised: March 2, 2020
Accepted: March 19, 2020
Article in press: March 19, 2020
Published online: April 6, 2020
Processing time: 103 Days and 6.3 Hours
Peer-review started: December 25, 2019
First decision: February 20, 2020
Revised: March 2, 2020
Accepted: March 19, 2020
Article in press: March 19, 2020
Published online: April 6, 2020
Processing time: 103 Days and 6.3 Hours
Core Tip
Core tip: In this study, we demonstrated that dickkopf-related protein-1 and tumor necrosis factor-α are effective in the diagnosis and treatment of ankylosing spondylitis and are risk factors for its recurrence. In addition, dickkopf-related protein-1 may be a potential target for future treatment of ankylosing spondylitis.