Case Control Study
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 6, 2020; 8(5): 864-873
Published online Mar 6, 2020. doi: 10.12998/wjcc.v8.i5.864
Study on the correlation and predictive value of serum pregnancy-associated plasma protein A, triglyceride and serum 25-hydroxyvitamin D levels with gestational diabetes mellitus
Zhuo Ren, Dong Zhe, Zhi Li, Xin-Ping Sun, Kai Yang, Li Lin
Zhuo Ren, Dong Zhe, Zhi Li, Kai Yang, Li Lin, Department of Obstetrics and Gynecology, Peking University International Hospital, Beijing 102206, China
Xin-Ping Sun, Department of Clinical Laboratory, Peking University International Hospital, Beijing 102206, China
Author contributions: Ren Z and Dong Z designed the research; Li Z performed the research; Sun XP analyzed the data; Yang K and Li L wrote the paper. Ren Z and Dong Z contributed equally to this work.
Institutional review board statement: This study was reviewed and approved by the Peking University International Hospital Ethics Committee.
Informed consent statement: All patients in our study provided informed consent.
Conflict-of-interest statement: The authors declare no conflict of interest.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Li Lin, PhD, Chief Physician, Department of Obstetrics and Gynecology, Peking University International Hospital, No. 1, Life Garden Road, Zhongguancun Life Park, Changping District, Beijing 102206, China.
Received: November 26, 2019
Peer-review started: November 26, 2019
First decision: December 30, 2019
Revised: January 6, 2020
Accepted: February 10, 2020
Article in press: February 10, 2020
Published online: March 6, 2020
Core Tip

Core tip: In the present study, the serum levels of pregnancy-associated plasma protein A, triglyceride, and 25-hydroxyvitamin D levels in early pregnancy were evaluated. The results showed that these three parameters are potential influencing factors and can provide a certain predictive value for the occurrence of gestational diabetes mellitus. These factors have high value in clinical application.