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World J Clin Cases. Sep 26, 2020; 8(18): 3978-3987
Published online Sep 26, 2020. doi: 10.12998/wjcc.v8.i18.3978
Hepatic epithelioid hemangioendothelioma: Update on diagnosis and therapy
Kai Kou, Yu-Guo Chen, Jian-Peng Zhou, Xiao-Dong Sun, Da-Wei Sun, Shu-Xuan Li, Guo-Yue Lv
Kai Kou, Yu-Guo Chen, Jian-Peng Zhou, Xiao-Dong Sun, Da-Wei Sun, Shu-Xuan Li, Guo-Yue Lv, Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China
Author contributions: Lv GY contributed to the conception of the study; Zhou JP, Sun XD, Sun DW, and Li SX contributed significantly to manuscript preparation; Kou K and Chen YG wrote the manuscript; all authors read and approved the final version for publication.
Supported by the Projects of Department of Science and Technology of Jilin Province, No. 20180622004JC.
Conflict-of-interest statement: The authors declare that they have no competing interests to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Guo-Yue Lv, PhD, Doctor, Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, No. 71 Xinmin Street, Changchun 130021, Jilin Province, China. kouxiuyangming@qq.com
Received: July 6, 2020
Peer-review started: July 6, 2020
First decision: August 8, 2020
Revised: August 12, 2020
Accepted: August 22, 2020
Article in press: August 22, 2020
Published online: September 26, 2020
Processing time: 77 Days and 10.5 Hours
Core Tip

Core Tip: In this work, we review the updated diagnosis and therapy of the hepatic epithelioid hemangioendothelioma, which is an extremely rare tumor of vascular origin with an incidence of < 0.1 per 100000 population. It is hard to differentiate from other liver lesions and there is no standard strategy for treating it based on its rarity. Our work helps to better understand and treat this rare disease.