Retrospective Study
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 6, 2020; 8(17): 3730-3742
Published online Sep 6, 2020. doi: 10.12998/wjcc.v8.i17.3730
Shear wave elastography may be sensitive and more precise than transient elastography in predicting significant fibrosis
Tian-Tian Yao, Jing Pan, Jian-Dan Qian, Hao Cheng, Yan Wang, Gui-Qiang Wang
Tian-Tian Yao, Jing Pan, Jian-Dan Qian, Hao Cheng, Yan Wang, Gui-Qiang Wang, Department of Infectious Diseases, Peking University First Hospital, Beijing 100034, China
Gui-Qiang Wang, Peking University International Hospital, Beijing 102206, China
Gui-Qiang Wang, the Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University, Hangzhou 310058, Zhejiang Province, China
Author contributions: Yao TT collected, analyzed and interpreted the data and contributed to writing the manuscript; Pan J collected and analyzed data; Qian JD and Cheng H contributed to the statistical analysis; Wang Y contributed to discussion and manuscript revision; Wang Y and Wang GQ designed, drafted and substantively revised the manuscript, and contributed to this work equally; all authors read and approved the final manuscript.
Supported by the National Natural Science Foundation of China, No. 81870417; Sub-Subject of the Major Projects of National Science and Technology, No. 2018ZX10302206, No. 2017ZX10203202 and No. 2017ZX10302201.
Institutional review board statement: The study was approved by the Ethics Committee of Peking University First Hospital and conformed to the guidelines set forth by the 1964 Declaration of Helsinki.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Gui-Qiang Wang, MD, PhD, Doctor, Professor, Department of Infectious Diseases, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China. john131212@sina.com
Received: January 8, 2020
Peer-review started: January 8, 2020
First decision: February 26, 2020
Revised: March 27, 2020
Accepted: July 15, 2020
Article in press: July 15, 2020
Published online: September 6, 2020
Core Tip

Core tip: Our study revealed that shear wave elastography (SWE) was less affected by influencing factors than transient elastography (TE). SWE may be more sensitive and more precise than TE in discriminating significant fibrosis (> F2). This modality might help identify chronic hepatitis B patients who may benefit from treatment. SWE may have broader clinical application prospects in routine standard examinations in hepatitis B virus patients.