Copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 26, 2020; 8(10): 1932-1938
Published online May 26, 2020. doi: 10.12998/wjcc.v8.i10.1932
Published online May 26, 2020. doi: 10.12998/wjcc.v8.i10.1932
Isolated colonic neurofibroma, a rare tumor: A case report and review of literature
Sara Ghoneim, Department of Internal Medicine, Case Western Reserve University at MetroHealth Medical Center, Cleveland, OH 44109, United States
Sonia Sandhu, Department of Hematology and Oncology, Cleveland Clinic Akron General, Cleveland, OH 44307, United States
Dalbir Sandhu, Division of Gastroenterology, Case Western Reserve University at MetroHealth Medical Center, Cleveland, OH 44109, United States
Author contributions: Ghoneim S, Sandhu S and Dalbir S wrote the manuscript and reviewed the literature; Ghoneim S is the article guarantor; all authors edited and revised the manuscript.
Informed consent statement: The patient provided informed consent for the publication of his case.
Conflict-of-interest statement: All authors have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE checklist (2016), and the manuscript was prepared and revised according to the CARE checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Sara Ghoneim, MD, Doctor, Department of Internal Medicine, Case Western Reserve University at MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, OH 44109, United States. saragho@gmail.com
Received: January 31, 2020
Peer-review started: January 31, 2020
First decision: April 8, 2020
Revised: April 24, 2020
Accepted: April 27, 2020
Article in press: April 27, 2020
Published online: May 26, 2020
Peer-review started: January 31, 2020
First decision: April 8, 2020
Revised: April 24, 2020
Accepted: April 27, 2020
Article in press: April 27, 2020
Published online: May 26, 2020
Core Tip
Core tip: Neurofibromas are composed of neural and connective tissue components. They are associated with hereditary syndromes such as neurofibromatosis type 1 and 2. They have systemic manifestations and may involve multiple organs. Malignant transformation of this tumor has been reported in literature. Isolated colonic neurofibroma is a rarely reported pathological entity. Clinical follow-up after surgical resection is recommended as solitary colonic neurofibromas might be the first sign of neurofibromatosis type 1.