Copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 26, 2020; 8(10): 1806-1817
Published online May 26, 2020. doi: 10.12998/wjcc.v8.i10.1806
Published online May 26, 2020. doi: 10.12998/wjcc.v8.i10.1806
Antiphospholipid syndrome and its role in pediatric cerebrovascular diseases: A literature review
Beata Sarecka-Hujar, Department of Basic Biomedical Science, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, Sosnowiec 41200, Poland
Ilona Kopyta, Department of Paediatric Neurology, School of Medicine in Katowice, Medical University of Silesia in Katowice, Sosnowiec 41200, Poland
Author contributions: Sarecka-Hujar B performed and collected the data, wrote the paper, prepared figures; Kopyta I performed and collected the data, wrote the paper.
Conflict-of-interest statement: There is no conflict of interest associated with any of the senior author or other coauthors contributed their efforts in this manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Beata Sarecka-Hujar, PhD, Adjunct Professor, Doctor, Department of Basic Biomedical Science, School of Pharmacy with the Division of Laboratory Medicine, Medical University of Silesia in Katowice, Kasztanowa Street 3, Sosnowiec 41200, Poland. bsarecka-hujar@sum.edu.pl
Received: December 29, 2019
Peer-review started: December 29, 2019
First decision: March 24, 2020
Revised: April 10, 2020
Accepted: April 27, 2020
Article in press: April 27, 2020
Published online: May 26, 2020
Peer-review started: December 29, 2019
First decision: March 24, 2020
Revised: April 10, 2020
Accepted: April 27, 2020
Article in press: April 27, 2020
Published online: May 26, 2020
Core Tip
Core tip: Antiphospholipid syndrome in children is a rare disorder. The most characteristic clinical presentation of antiphospholipid syndrome (APS) in the pediatric population is venous thrombosis and arterial thrombosis causing ischemic stroke. However, no diagnostic criteria for pediatric APS exist at present, which probably results in an underestimation of the problem. We discussed data concerning APS in children and its role in cerebrovascular diseases, including pediatric arterial ischemic stroke, migraine and cerebral venous thrombosis.