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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 6, 2020; 8(1): 179-187
Published online Jan 6, 2020. doi: 10.12998/wjcc.v8.i1.179
Published online Jan 6, 2020. doi: 10.12998/wjcc.v8.i1.179
Calcitonin-negative neuroendocrine tumor of the thyroid with metastasis to liver-rare presentation of an unusual tumor: A case report and review of literature
Huai-Jie Cai, Han Wang, Nan Cao, Bin Huang, The Fourth Clinical Medicine College, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China
Fan-Lei Kong, Li-Ren Lu, Ya-Yuan Huang, Wei Wang, Department of Ultrasound, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang Province, China
Author contributions: Cai HJ participated in the design of the report, analyzed the data, and wrote the paper; Kong FL, Lu LR, and Huang YY collected the medical imaging materials; Wang H, Cao N, Huang B, and Wang W designed the report and performed the preliminary revision of the article.
Informed consent statement: Consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Wei Wang, MA, Chief Physician, Department of Ultrasound, Affiliated Hangzhou First people’s Hospital, Zhejiang University School of Medicine, No. 261, Huansha Road, Shangcheng District, Hangzhou 310006, Zhejiang Province, China. wangwei8328003@163.com
Received: October 15, 2019
Peer-review started: October 15, 2019
First decision: November 13, 2019
Revised: November 22, 2019
Accepted: November 30, 2019
Article in press: November 30, 2019
Published online: January 6, 2020
Processing time: 83 Days and 12.7 Hours
Peer-review started: October 15, 2019
First decision: November 13, 2019
Revised: November 22, 2019
Accepted: November 30, 2019
Article in press: November 30, 2019
Published online: January 6, 2020
Processing time: 83 Days and 12.7 Hours
Core Tip
Core tip: Calcitonin-negative neuroendocrine tumor of the thyroid is an extremely rare disorder, with past literature mostly documenting case reports. Medical imaging has revealed no specific manifestations, and current diagnosis mainly depends on pathological biopsy findings. The prognosis of thyroid neuroendocrine tumors is poorer than that of other thyroid tumors. Transcatheter arterial chemoembolization is not effective in cases of liver metastasis, and no improved treatments have been developed to date. This article provides a complete introduction of this case report with an aim to provide a meaningful reference for future research and trials.