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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 6, 2020; 8(1): 103-109
Published online Jan 6, 2020. doi: 10.12998/wjcc.v8.i1.103
Published online Jan 6, 2020. doi: 10.12998/wjcc.v8.i1.103
Sclerosing angiomatoid nodular transformation of the spleen, a rare cause for splenectomy: Two case reports
Sophia Chikhladze, Ann-Kathrin Lederer, Stefan Fichtner-Feigl, Uwe A Wittel, Department of General and Visceral Surgery, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg 79106, Germany
Ann-Kathrin Lederer, Center for Complementary Medicine, Department of Infection Prevention and Hospital Epidemiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg 79106, Germany
Martin Werner, Konrad Aumann, Institute of Surgical Pathology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg 79106, Germany
Author contributions: Chikhladze S and Aumann K initiated the study and collected the cases; Wittel UA, Fichtner-Feigl S, and Chikhladze S performed the surgery; Werner M and Aumann K performed histological evaluations; Lederer AK wrote the manuscript with the help of Chikhladze S and Aumann K; Wittel UA, Fichtner-Feigl S, and Werner M revised the manuscript.
Informed consent statement: Informed written consent was obtained from the patients for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Sophia Chikhladze, MD, Surgeon, Department of General and Visceral Surgery, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, Freiburg 79106, Germany. sophia.chikhladze@uniklinik-freiburg.de
Received: October 18, 2019
Peer-review started: October 18, 2019
First decision: November 4, 2019
Revised: November 12, 2019
Accepted: November 20, 2019
Article in press: November 20, 2019
Published online: January 6, 2020
Peer-review started: October 18, 2019
First decision: November 4, 2019
Revised: November 12, 2019
Accepted: November 20, 2019
Article in press: November 20, 2019
Published online: January 6, 2020
Core Tip
Core tip: We are presenting two cases of clinical evident sclerosing angiomatoid nodular transformation (SANT) and discuss the challenge of clinical non-operative management of small and asymptomatic splenic lesions. SANT is a benign vascular lesion of unknown etiology occurring in the spleen and does not appear to be related to age, gender, or pre-existing illnesses, although some reports have reported a higher frequency in women. SANT is an incidental histologically finding after splenectomy, and there is no guideline for treatment of SANT.