Case Report
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 26, 2019; 7(4): 500-507
Published online Feb 26, 2019. doi: 10.12998/wjcc.v7.i4.500
Therapeutic plasma exchange and continuous renal replacement therapy for severe hyperthyroidism and multi-organ failure: A case report
Jun-Hui Ba, Ben-Quan Wu, Yan-Hong Wang, Yun-Feng Shi
Jun-Hui Ba, Ben-Quan Wu, Yan-Hong Wang, Yun-Feng Shi, Department of Medical Intensive Unit, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China
Author contributions: Ba JH and Wu BQ designed the report; Wang YH and Shi YF collected the patient’s clinical data; Ba JH and Wu BQ analyzed the data and wrote the paper.
Informed consent statement: Consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Ben-Quan Wu, MD, Professor, Director, Department of Medical Intensive Unit, the Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tian He Road, Guangzhou 510630, Guangdong Province, China. zswbq@163.com
Telephone: +86-020-85253479 Fax: +86-020-85253479
Received: November 12, 2018
Peer-review started: November 13, 2018
First decision: November 27, 2018
Revised: December 21, 2018
Accepted: December 29, 2018
Article in press: December 30, 2018
Published online: February 26, 2019
Processing time: 106 Days and 21.3 Hours
Core Tip

Core tip: Severe hyperthyroidism accompanied with multiple organ failure has been previously reported but is rare. In this case report, acute liver failure like our patient is a very unusual form of presentation. Considering the patient’s medical history, propylthiouracil-induced hepatotoxicity could not be excluded. Therapeutic plasma exchange combined with continuous renal replacement therapy were performed, and successfully stabilized the patient. We suggest that the early application of blood purification technology is feasible in critically patients with severe hyperthyroidism.