Copyright
©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 26, 2019; 7(24): 4334-4341
Published online Dec 26, 2019. doi: 10.12998/wjcc.v7.i24.4334
Published online Dec 26, 2019. doi: 10.12998/wjcc.v7.i24.4334
Epstein-Barr virus-positive post-transplant lymphoproliferative disordepresenting as hematochezia and enterobrosis in renal transplant recipients in China: A report of two cases
Ze-Jia Sun, Xiao-Peng Hu, Bo-Han Fan, Wei Wang, Institute of Urology, Capital Medical University, Department of Urology, Beijng Chao-Yang Hospital, Capital Medical University, Beijing 100030, China
Author contributions: All of the authors participated in the writing of the article.
Supported by the National Natural Science Foundation of China , No. 81771720 .
Informed consent statement: We obtained the informed consent from the patients.
Conflict-of-interest statement: We declare that there is no conflict of interest related to this report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Wei Wang, PhD, Chief Doctor, Professor, Surgeon, Institute of Urology, Capital Medical University, Department of Urology, Capital Medical University Beijing Chaoyang Hospital, 7th Floor, Building B, 8 Workers Stadium South Road, Beijing 100030, China. sunzejia1002@sina.com
Telephone: +86-13910790920
Received: May 10, 2019
Peer-review started: May 14, 2019
First decision: September 9, 2019
Revised: October 22, 2019
Accepted: November 14, 2019
Article in press: November 14, 2019
Published online: December 26, 2019
Peer-review started: May 14, 2019
First decision: September 9, 2019
Revised: October 22, 2019
Accepted: November 14, 2019
Article in press: November 14, 2019
Published online: December 26, 2019
Core Tip
Core tip: Post-transplant lymphoproliferative disorder (PTLD) is a rare severe complication after renal transplantation, with an incidence of approximately 0.3%-2.0% in patients undergoing renal transplantation. We report two Epstein-Barr virus-positive PTLD cases whose main clinical manifestations were digestive tract symptoms. As both of them admitted to our hospital because of extranodal infiltration symptoms, we did not suspect of PTLD until the pathology confirmation. We also discuss the virological monitoring, clinical characteristics, diagnosis, and treatment of PTLD.