Copyright
©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 26, 2019; 7(24): 4270-4276
Published online Dec 26, 2019. doi: 10.12998/wjcc.v7.i24.4270
Published online Dec 26, 2019. doi: 10.12998/wjcc.v7.i24.4270
Acute appendicitis in a patient after a uterus transplant: A case report
Jakub Kristek, Michal Kudla, Jaroslav Chlupac, Robert Novotny, Libor Janousek, Jiri Fronek, Department of Transplant Surgery, Institute for Clinical and Experimental Medicine, Prague 140 21, Czech Republic
Jakub Kristek, Jaroslav Chlupac, Jiri Fronek, Department of Anatomy, Second Faculty of Medicine, Charles University, Prague 150 06, Czech Republic
Tomas Mirejovsky, Department of Clinical and Transplant Pathology, Institute for Clinical and Experimental Medicine, Prague 140 21, Czech Republic
Libor Janousek, First Faculty of Medicine, Charles University, Prague 121 08, Czech Republic
Author contributions: Kristek J wrote the manuscript and analyzed the data. Kudla M operated on the patient. Chlupac J and Novotny R co-analyzed the data and provided consultations regarding the risk of thrombosis. Mirejovsky T provided the histological image. Janousek L and Fronek J designed and ran the uterus transplantation trial and provided consultations regarding this case.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Jakub Kristek, MD, Department of Anatomy, Second Faculty of Medicine, Charles University, V Uvalu 84, Prague 150 06, Czech Republic. krsj@ikem.cz
Telephone: +420-23-6054105 Fax: +420-23-6052822
Received: September 20, 2019
Peer-review started: September 20, 2019
First decision: October 20, 2019
Revised: November 7, 2019
Accepted: November 15, 2019
Article in press: November 15, 2019
Published online: December 26, 2019
Processing time: 95 Days and 17.7 Hours
Peer-review started: September 20, 2019
First decision: October 20, 2019
Revised: November 7, 2019
Accepted: November 15, 2019
Article in press: November 15, 2019
Published online: December 26, 2019
Processing time: 95 Days and 17.7 Hours
Core Tip
Core tip: Herein, we present a unique report of a woman with a viable transplanted uterus graft who was suffering from concurrent Clostridium difficile colitis and acute appendicitis. The differential diagnosis in an immunosuppressed patient may be complex, and a high index of suspicion of an atypical course of acute abdomen should be maintained in immunosuppressed patients. Sometimes, more than one synchronous pathological condition may be present. This case highlights the ultimate importance of focusing on the achievement of successful embryo transfer in the uterus transplantation recipients as soon as possible since they are vulnerable to a multitude of possible complications.