Systematic Review
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 26, 2019; 7(24): 4254-4269
Published online Dec 26, 2019. doi: 10.12998/wjcc.v7.i24.4254
Chronic pain, posttraumatic stress disorder, and opioid intake: A systematic review
Alicia E López-Martínez, Ángela Reyes-Pérez, Elena Rocío Serrano-Ibáñez, Rosa Esteve, Carmen Ramírez-Maestre
Alicia E López-Martínez, Ángela Reyes-Pérez, Elena Rocío Serrano-Ibáñez, Rosa Esteve, Carmen Ramírez-Maestre, Facultad de Psicología, Instituto de Investigaciones Biomédicas (IBIMA), Universidad de Málaga, Málaga 29071, Spain
Author contributions: All authors equally contributed to this paper.
Conflict-of-interest statement: The authors have no conflict of interest for this manuscript.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Elena Rocío Serrano-Ibáñez, MSc, PhD, Postdoctoral Fellow, Facultad de Psicología, Instituto de Investigaciones Biomédicas (IBIMA), Universidad de Málaga, Campus de Teatinos, Málaga 29071, Spain. elenarserrano@uma.es
Telephone: +34-95-63578781
Received: April 13, 2019
Peer-review started: April 15, 2019
First decision: September 9, 2019
Revised: October 17, 2019
Accepted: November 26, 2019
Article in press: November 26, 2019
Published online: December 26, 2019
Processing time: 257 Days and 3.5 Hours
Core Tip

Core tip: In the management of chronic pain, co-morbid posttraumatic stress disorder (PTSD) plays a critical role in opioid misuse or abuse. The present systematic review found that the study participants with comorbid PTSD and chronic non-cancer pain received higher doses of opioids, received more than 1 type of opioid concurrently, and were more likely to receive chronic opioids.