Observational Study
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 26, 2019; 7(22): 3751-3756
Published online Nov 26, 2019. doi: 10.12998/wjcc.v7.i22.3751
Relationship between homocysteine level and prognosis of elderly patients with acute ischemic stroke treated by thrombolysis with recombinant tissue plasminogen activator
Juan Li, Fan Zhou, Feng-Xue Wu
Juan Li, Feng-Xue Wu, Department of General Practice, Jingzhou Central Hospital, Jingzhou 434100, Hubei Province, China
Fan Zhou, Department of Neurology, Jingzhou Central Hospital, Jingzhou 434100, Hubei Province, China
Author contributions: Li J, Zhou F, and Wu FX contributed to study design and manuscript drafting; Li J, Zhou F, and Wu FX revised the manuscript; all authors proofed the manuscript for its publication.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Jingzhou Central Hospital.
Informed consent statement: All study participants provided informed consent.
Conflict-of-interest statement: There are no conflicts of interest.
Data sharing statement: No additional data are available.
STROBE statement: The authors revised the manuscript according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Feng-Xue Wu, MD, Chief Doctor, Director, Department of General Practice, Jingzhou Central Hospital, No. 60, Jingzhong Road, Jingzhou 434100, Hubei Province, China. 37016653@qq.com
Received: September 7, 2019
Peer-review started: September 7, 2019
First decision: September 23, 2019
Revised: October 31, 2019
Accepted: November 14, 2019
Article in press: November 14, 2019
Published online: November 26, 2019
Core Tip

Core tip: Acute ischemic stroke (AIS) is one of the most common strokes that occur in the clinical practice. It is mainly caused by cerebral blood flow disorders, which further leads to ischemic brain necrosis or encephalomalacia. Studies are still rare and little is known about the relationship of Hcy level with the prognosis. The present study analyzed the relationship between homocysteine level and the prognosis of elderly patients with AIS after the administration of recombinant tissue plasminogen activator.