Case Report
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 26, 2019; 7(2): 242-252
Published online Jan 26, 2019. doi: 10.12998/wjcc.v7.i2.242
Collision carcinoma of squamous cell carcinoma and small cell neuroendocrine carcinoma of the larynx: A case report and review of the literature
Qi Yu, Ya-Lian Chen, Shui-Hong Zhou, Zhe Chen, Yang-Yang Bao, Han-Jin Yang, Hong-Tian Yao, Ling-Xiang Ruan
Qi Yu, Ya-Lian Chen, Shui-Hong Zhou, Zhe Chen, Yang-Yang Bao, Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Han-Jin Yang, Hong-Tian Yao, Department of Pathology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Ling-Xiang Ruan, Department of Radiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Author contributions: Zhou SH designed the report; Yu Q, Chen YL, Chen Z, and Bao YY collected and analyzed the patient’s clinical data; Yu Q and Chen YL drafted and revised the paper; Yang HJ and Yao HT provided pathological analysis; Ruan LX provided image analysis.
Informed consent statement: Consent was obtained from relatives of the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read CARE Checklist (2016) and checked the manuscript accordingly.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Shui-Hong Zhou, MD, Professor, Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. 1190051@zju.edu.cn
Telephone: +86-571-87236894 Fax: +86-571-87236895
Received: September 22, 2018
Peer-review started: September 24, 2018
First decision: October 25, 2018
Revised: November 23, 2018
Accepted: December 7, 2018
Article in press: December 8, 2018
Published online: January 26, 2019
Processing time: 126 Days and 1.7 Hours
Core Tip

Core tip: Collision carcinoma is rare in clinical practice, especially in the head and neck region. In this paper, we report a case of squamous cell carcinoma and neuroendocrine carcinoma colliding in the larynx and review 12 cases of collision carcinoma in the head and neck to further understand collision carcinoma, including its definition, diagnosis, and treatment.