Copyright
©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 26, 2019; 7(18): 2687-2703
Published online Sep 26, 2019. doi: 10.12998/wjcc.v7.i18.2687
Published online Sep 26, 2019. doi: 10.12998/wjcc.v7.i18.2687
Predictors of rebleeding and in-hospital mortality in patients with nonvariceal upper digestive bleeding
Daniela Cornelia Lazăr, Department of Internal Medicine I, University Medical Clinic, University of Medicine and Pharmacy “Victor Babeş”, Timişoara 300041, Timiş County, Romania
Sorin Ursoniu, Department of Public Health and Health Management, University of Medicine and Pharmacy “Victor Babeş”, Timişoara 300041, Timiş County, Romania
Adrian Goldiş, Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy “Victor Babeş”, Timişoara 300041, Timiş County, Romania
Author contributions: All the authors contributed equally to this work.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of the University of Medicine and Pharmacy “Victor Babeş”, Timişoara.
Informed consent statement: Patients were not required to give informed consent for the study because the analysis was retrospective, and it used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: The authors have no conflict of interest to report.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Daniela Cornelia Lazăr, MD, PhD, Senior Lecturer, Department of Internal Medicine I, University Medical Clinic, University of Medicine and Pharmacy “Victor Babeş”, Piata Eftimie Murgu No. 2, Timişoara 300041, Timiş County, Romania. lazar.daniela@umft.ro
Telephone: +40-256-220484 Fax: +40-256-220484
Received: June 25, 2019
Peer-review started: June 25, 2019
First decision: July 20, 2019
Revised: August 16, 2019
Accepted: August 27, 2019
Article in press: August 26, 2019
Published online: September 26, 2019
Peer-review started: June 25, 2019
First decision: July 20, 2019
Revised: August 16, 2019
Accepted: August 27, 2019
Article in press: August 26, 2019
Published online: September 26, 2019
Core Tip
Core tip: Because the rate of morbidity and mortality in patients with nonvariceal upper digestive bleeding (NVUDB) remains high, our retrospective study aims to identify clinical and paraclinical parameters associated with the risk of rebleeding and death in these patients. Our data showed that the Rockall score was associated with both rebleeding and death. The presence of comorbidities was associated with an increased risk of in-hospital mortality; among them, sepsis was associated with the highest risk. Identification of the risk factors for poor outcomes in patients with NVUDB proved to be associated with an improvement in management and, subsequently, in patient outcomes.