Copyright
©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 6, 2019; 7(17): 2556-2561
Published online Sep 6, 2019. doi: 10.12998/wjcc.v7.i17.2556
Published online Sep 6, 2019. doi: 10.12998/wjcc.v7.i17.2556
Severe serous cavity bleeding caused by acquired factor V deficiency associated with lymphatic leakage in a hemodialysis patient: A case report
Wen-Bo Zhao, Yan-Ru Chen, Hong-Chun Lin, Department of Nephrology,The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China
Dan Luo, Hui Peng, Department of Nephrology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China
Bing Long, Department of Hematology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China
Zhen-Yu Wu, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China
Author contributions: Zhao WB was the patient’s renal physician, reviewed the literature and contributed to manuscript drafting; Chen YR reviewed the literature and contributed to manuscript drafting; Luo D and Lin HC performed the interpretation and contributed to manuscript drafting; Wu ZY analyzed data and interpreted the findings of statistical analysis; Long B performed the blood diseases consultation, reviewed the literature and drafted the manuscript; Peng H was responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2013), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Hui Peng, MD, PhD, Professor, Department of Nephrology, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Road, Guangzhou 510630, Guangdong Province, China. pengh@mail.susu.edu.cn
Telephone: +86-20-85252865
Received: April 24, 2019
Peer-review started: May 8, 2019
First decision: May 31, 2019
Revised: July 30, 2019
Accepted: August 20, 2019
Article in press: August 20, 2019
Published online: September 6, 2019
Processing time: 136 Days and 0 Hours
Peer-review started: May 8, 2019
First decision: May 31, 2019
Revised: July 30, 2019
Accepted: August 20, 2019
Article in press: August 20, 2019
Published online: September 6, 2019
Processing time: 136 Days and 0 Hours
Core Tip
Core tip: Acquired factor V deficiency (AFVD) is a rare secondary hemorrhagic disease, which can lead to serious bleeding disorder. We report a new AVFD case of a hemodialysis patient with severe serous cavity hemorrhagic effusion, associated with potentially secondary to lymphatic leakage, and factor V inhibitor detection is negative. This is the first report regarding the association between coagulation factor V deficiency and lymphatic drainage in hemodialysis patient of chronic kidney disease patient. Careful follow-up of blood coagulation is needed in patients under the treatment of lymphatic drainage.