Systematic Reviews
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 26, 2019; 7(12): 1430-1443
Published online Jun 26, 2019. doi: 10.12998/wjcc.v7.i12.1430
Non-albicans Candida prosthetic joint infections: A systematic review of treatment
Christos Koutserimpas, Stylianos G Zervakis, Sofia Maraki, Kalliopi Alpantaki, Argyrios Ioannidis, Diamantis P Kofteridis, George Samonis
Christos Koutserimpas, Department of Orthopaedics and Traumatology, “251” Hellenic Air Force General Hospital of Athens, Athens 11525, Greece
Stylianos G Zervakis, Diamantis P Kofteridis, George Samonis, Department of Internal Medicine, University Hospital of Heraklion, Crete, Heraklion 71110, Greece
Sofia Maraki, Department of Clinical Microbiology and Microbial Pathogenesis, University Hospital of Heraklion, Crete, Heraklion 71110, Greece
Kalliopi Alpantaki, Department of Materials Science and Technology, University of Crete, Heraklion, Heraklion 71110, Greece
Argyrios Ioannidis, Department of General Surgery, “Sismanoglion” General Hospital of Athens, Athens 15126, Greece
Author contributions: Koutserimpas C, Zervakis SG, Alpantaki K and Samonis G designed the research; Zervakis SG, Maraki S and Kofteridis DP performed the research; Koutserimpas C and Ioannidis A contributed new reagents/analytic tools; Koutserimpas C and Ioannidis A analyzed the data; Koutserimpas C, Zervakis SG, Alpantaki K and Samonis G wrote the paper.
Conflict-of-interest statement: The authors declare no conflict of interest.
PRISMA 2009 Checklist statement: PRISMA 2009 Checklist statement is provided.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Christos Koutserimpas, MD, Doctor, Department of Orthopaedics and Traumatology, "251" Hellenic Air Force General Hospital of Athens, P. Kanellopoulou Av., Athens 11525, Greece. chrisku91@hotmail.com
Telephone: +30-694-8712130
Received: January 22, 2019
Peer-review started: January 23, 2019
First decision: March 10, 2019
Revised: March 16, 2019
Accepted: April 19, 2019
Article in press: April 19,2019
Published online: June 26, 2019
Processing time: 155 Days and 10.7 Hours
Core Tip

Core tip: Non-albicans Candida prosthetic joint infections (PJIs) are rare, and no clear guidelines exist regarding the treatment of these infections. The purpose of this study was to clarify, by reviewing current published cases, the treatment options of non-albicans Candida PJIs and, possibly, to improve the medical and surgical care of such cases. A literature review of all existing non-albicans Candida PJIs cases through April 2018 was conducted. The combination of two stage revision arthroplasty and administration of prolonged antifungal therapy after initial resection arthroplasty is suggested on the basis of limited data.