Observational Study
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 6, 2019; 7(1): 49-57
Published online Jan 6, 2019. doi: 10.12998/wjcc.v7.i1.49
Value of contrast-enhanced ultrasound combined with elastography in evaluating cervical lymph node metastasis in papillary thyroid carcinoma
Wei Jiang, Hong-Yan Wei, Hai-Yan Zhang, Qiu-Luan Zhuo
Wei Jiang, Hong-Yan Wei, Hai-Yan Zhang, Qiu-Luan Zhuo, Department of Ultrasound, Shenzhen Nanshan District People’s Hospital, Shenzhen 518052, Guangdong Province, China
Author contributions: Jiang W and Wei HY designed the research; Jiang W and Zhang HY performed the research; Zhuo QL contributed new analytic tools; Jiang W analyzed the data; and Jiang W, Wei HY and Zhuo QL wrote the paper.
Supported by Shenzhen Science and Technology Plan Funding Project, No. 201102125.
Institutional review board statement: The study was reviewed and approved by the ethics committee of Shenzhen Nanshan District People’s Hospital.
Informed consent statement: All patients gave informed consent.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Wei Jiang, MD, Doctor, Department of Ultrasound, Shenzhen Nanshan District People’s Hospital, No. 89, Taoyuan Road, Nanshan District, Shenzhen 518052, Guangdong Province, China. jwszdr@126.com
Telephone: +96-130-26628099
Received: November 9, 2018
Peer-review started: November 12, 2018
First decision: November 28, 2018
Revised: December 1, 2018
Accepted: December 12, 2018
Article in press: December 12, 2018
Published online: January 6, 2019
Core Tip

Core tip: Cervical lymph node metastasis of papillary thyroid carcinoma affects the prognosis and treatment of patients. Currently, contrast-enhanced ultrasound and ultrasound elastography have been gradually applied to the diagnosis of cervical lymph node metastasis. However, it is not clear whether contrast-enhanced ultrasound and elastography combined with conventional ultrasound improve the accuracy of lymph node metastasis diagnosis. In this study, we analyzed the differences among conventional ultrasound, contrast-enhanced ultrasound and elastography in metastatic and reactive lymph nodes, and used a logistic regression model to fit the probability equation of lymph node metastasis to improve the diagnostic accuracy of metastatic lymph nodes.