Ren X, Zhu CL, Qin XF, Jiang H, Xia T, Qu YP. Co-occurrence of IPMN and malignant IPNB complicated by a pancreatobiliary fistula: A case report and review of the literature. World J Clin Cases 2019; 7(1): 102-108 [PMID: 30637259 DOI: 10.12998/wjcc.v7.i1.102]
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Xu Ren, Tian Xia, Digestive Disease Hospital of Heilongjiang Provincial Hospital, Harbin 150001, Heilongjiang Province, China
Chun-Lan Zhu, Xu-Fu Qin, The Second Digestive Department, Digestive Disease Hospital of Heilongjiang Provincial Hospital, Harbin 150001, Heilongjiang Provice, China
Hong Jiang, Department of Pathology of Heilongjiang Provincial Hospital, Harbin 150001, Heilongjiang Provice, China
Yong-Ping Qu, Digestive Endoscopy Center, Digestive Disease Hospital of Heilongjiang Provincial Hospital, Harbin 150001, Heilongjiang Provice, China
Author contributions: Ren X substantially contributed to the conception and design of the study and the acquisition, analysis, and interpretation of the data; Zhu CL, Qin XF, Jiang H, Xia T, and Qu YP contributed to drafting the article or making critical revisions related to important intellectual content of the manuscript; All authors approved the final version of the article to be published.
Informed consent statement: The patient provided written informed consent.
Conflict-of-interest statement: All authors declare no conflicts of interest.
CARE Checklist (2016) statement: All authors read, prepared, and revised the manuscript based on the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Received: September 27, 2018 Peer-review started: September 27, 2018 First decision: November 2, 2018 Revised: December 6, 2018 Accepted: December 7, 2018 Article in press: December 8, 2018 Published online: January 6, 2019 Processing time: 99 Days and 3.6 Hours
Core Tip
Core tip: We report a patient with an extremely rare co-occurrence of intraductal papillary mucinous neoplasm (IPMN) and malignant intraductal papillary neoplasm of the bile duct (IPNB) accompanied with a pancreatobiliary fistula. The etiology of biliopancreatic duct dilatations could not be identified by radiologic imaging. After the patient underwent endoscopic retrograde cholangiopancreatography, the presence of a pancreatobiliary fistula was revealed by pancreatography. SpyGlass cholangiopancreatoscopy showed multiple papillary neoplasms in the pancreaticobiliary duct. In addition, SpyGlass was able to identify a pancreatobiliary fistula. The patient was diagnosed with benign IPMN and malignant IPNB. Different histological subtypes for both IPMN and IPNB were also identified. Radical resection on the patient achieved excellent results.