Case Control Study
Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 26, 2018; 6(14): 753-758
Published online Nov 26, 2018. doi: 10.12998/wjcc.v6.i14.753
Benefits of the Seattle biopsy protocol in the diagnosis of Barrett’s esophagus in a Chinese population
Shou-Wu Lee, Han-Chung Lien, Chi-Sen Chang, Ming-Xian Lin, Chung-Hsin Chang, Chung-Wang Ko
Shou-Wu Lee, Han-Chung Lien, Chi-Sen Chang, Ming-Xian Lin, Chung-Hsin Chang, Chung-Wang Ko, Division of Gastroenterology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung 40705, Taiwan
Shou-Wu Lee, Chi-Sen Chang, Department of Internal Medicine, Chung Shan Medical University, Taichung 40201, Taiwan
Han-Chung Lien, Chung-Wang Ko, Department of Internal Medicine, National Yang-Ming University, Taipei 11221, Taiwan
Author contributions: Lee SW and Lien HC contributed equally to this work; Lee SW, Lien HC, Chang CS and Lin MX designed the research; Lee SW, Lien HC, Lin MX, Chang CH and Ko CW performed the research; Lee SW contributed analytic tools; Lee SW and Chang CH analyzed the data; Lee SW and Lien HC wrote the paper.
Institutional review board statement: This study was reviewed and approved by the Taichung Veteran General Hospital Institutional Review Board Committee.
Informed consent statement: Patients were required to give informed consent, and clinical data were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All authors declare no conflicts of interest related to this study.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Shou-Wu Lee, MD, PhD, Assistant Professor, Division of Gastroenterology, Department of Internal Medicine, Taichung Veterans General Hospital, 1650 Taiwan Boulevard, Sec. 4, Taichung 40705, Taiwan. ericest@vghtc.gov.tw
Telephone: +886-4-23592525-3306 Fax: +886-4-23595046
Received: July 13, 2018
Peer-review started: July 13, 2018
First decision: July 24, 2018
Revised: September 4, 2018
Accepted: October 17, 2018
Article in press: October 16, 2018
Published online: November 26, 2018
Processing time: 136 Days and 21.3 Hours
Core Tip

Core tip: While comparing the diagnosis of Barrett’s esophagus in a Chinese population via narrow-band imaging-targeted biopsy or the Seattle protocol-guided biopsy, the sensitivity of intestinal metaplasia detection was 69.2% and 78.5%, respectively. The number of detectable dysplasias increased from one case via the narrow-band imaging-targeted biopsy to five cases via the Seattle protocol-guided biopsy. These results concluded that the Seattle protocol identified more cases with dysplastic tissues.