Natural killer cells activity in a metastatic colorectal cancer patient with complete and long lasting response to therapy
Alessandro Ottaiano, Monica Capozzi, Salvatore Tafuto, Antonio Avallone, Department of Abdominal Oncology, Istituto Nazionale per lo Studio e la Cura dei Tumori “Fondazione Giovanni Pascale” - I.R.C.C.S., Naples 80131, Italy
Maria Napolitano, Stefania Scala, Immunology Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori “Fondazione Giovanni Pascale” - I.R.C.C.S., Naples 80131, Italy
Author contributions: Ottaiano A contributed in planning, analysis, discussing and writing of the manuscript; Napolitano M, Avallone A and Scala S contributed in planningdesigning and performing experiments and discussing of the manuscript; Capozzi M and Tafuto S contributed in planning and writing of the manuscript.
Institutional review board statement: This case report was exempt from the Institutional Review Board standards at I.R.C.C.S.
Informed consent statement: The patient involved in this study gave her written informed consent authorizing use and disclosure of his protected health information.
Conflict-of-interest statement: We declare no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Alessandro Ottaiano, Department of Abdominal Oncology, Istituto Nazionale per lo Studio e la Cura dei Tumori “Fondazione Giovanni Pascale” - I.R.C.C.S., via M. Semmola, Naples 80131, Italy. email@example.com
Telephone: +39-81-5903510 Fax: +39-81-7714224
Received: December 16, 2016
Peer-review started: December 19, 2016
First decision: March 28, 2017
Revised: May 24, 2017
Accepted: June 12, 2017
Article in press: June 13, 2017
Published online: November 16, 2017