Retrospective Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 16, 2016; 4(10): 310-317
Published online Oct 16, 2016. doi: 10.12998/wjcc.v4.i10.310
Efficacy of Japanese traditional (Kampo) medicine for treating chemotherapy-induced peripheral neuropathy: A retrospective case series study
Yumiko Kimata, Keiko Ogawa, Hideki Okamoto, Atsushi Chino, Takao Namiki
Yumiko Kimata, Hideki Okamoto, Takao Namiki, Department of Japanese-Oriental (Kampo) Medicine, Chiba University School of Medicine, Chiba 260-8670, Japan
Keiko Ogawa, Department of Japanese-Traditional (Kampo) Medicine, Kanazawa University Hospital, Ishikawa 920-8641, Japan
Atsushi Chino, Department of Japanese-Oriental (Kampo) Medicine, Chiba Central Medical Center, Chiba 264-0017, Japan
Author contributions: Kimata Y, Ogawa K and Okamoto H designed the report, analyzed the data, and wrote the paper; Chino A and Namiki T collected the patients’ clinical data and supervised the paper.
Institutional review board statement: This case report was exempt from the Ethics Committee of Chiba University Hospital.
Informed consent statement: This is a retrospective case series study. There was no way to get touch with all patients involved in this study so we had been notifying them of this study on our department’s website.
Conflict-of-interest statement: Kimata Y, Ogawa K, Okamoto H, and Namiki T got a grant as Research Support from Tsumua Co. Atsushi Chino has no conflict of interests regarding the publication of this paper.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Hideki Okamoto, MD, Associate Professor, Department of Japanese-Oriental (Kampo) Medicine, Chiba University School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan.
Telephone: +81-43-2262984 Fax: +81-43-2262985
Received: April 27, 2016
Peer-review started: April 28, 2016
First decision: June 16, 2016
Revised: July 14, 2016
Accepted: August 6, 2016
Article in press: August 8, 2016
Published online: October 16, 2016
Core Tip

Core tip: Our single-institution 5-year retrospective case series study revealed that Japanese traditional (Kampo) medicine was beneficial in 83.3% of patients with cancer chemotherapy-induced peripheral neuropathy that is refractory to conventional medicine. The most frequently used formula was goshajinkigan, followed by hachimijiogan and keishibukuryogan.