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Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 16, 2015; 3(7): 614-624
Published online Jul 16, 2015. doi: 10.12998/wjcc.v3.i7.614
Cervical cancer screening: A never-ending developing program
Ciro Comparetto, Franco Borruto
Ciro Comparetto, Division of Obstetrics and Gynecology, City Hospital, Azienda USL 4, 59100 Prato, Italy
Franco Borruto, Obstetrics and Gynecology, Princess Grace Hospital, 98000 Principality of Monaco, Italy
Author contributions: Comparetto C and Borruto F wrote and revised the paper.
Conflict-of-interest statement: In the interests of transparency, the authors declare no conflicting interests (including but not limited to commercial, personal, political, intellectual, or religious interests) related to this work.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Ciro Comparetto, MD, Division of Obstetrics and Gynecology, City Hospital, Azienda USL 4, Via Suor Niccolina Infermiera 20, 59100 Prato, Italy. cicomp@tin.it
Telephone: +39-347-4856799 Fax: +39-055-6122154
Received: January 6, 2014
Peer-review started: January 9, 2014
First decision: March 12, 2014
Revised: May 28, 2015
Accepted: June 9, 2015
Article in press: June 11, 2015
Published online: July 16, 2015
Processing time: 566 Days and 20.9 Hours
Core Tip

Core tip: Most cases of cervical cancer are preventable and, if caught early, highly curable. Despite this, cervical cancer is the second most common cause of cancer death and a leading cause of morbidity in women worldwide. Unfortunately, cure is less likely when the disease is diagnosed at an advanced stage. Although the human papillomavirus is considered the major causative agent of cervical cancer, yet the viral infection alone is not sufficient for cancer progression.