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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 16, 2015; 3(2): 148-155
Published online Feb 16, 2015. doi: 10.12998/wjcc.v3.i2.148
Published online Feb 16, 2015. doi: 10.12998/wjcc.v3.i2.148
Role of coronary physiology in the contemporary management of coronary artery disease
Neil Ruparelia, Rajesh K Kharbanda, Oxford Heart Centre, John Radcliffe Hospital, OX3 9DU Oxford, United Kingdom
Author contributions: Ruparelia N and Kharbanda RK both devised, drafted and revised the manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Rajesh K Kharbanda, Oxford Heart Centre, John Radcliffe Hospital, Headley Way, OX3 9DU Oxford, United Kingdom. rajesh.kharbanda@ouh.nhs.uk
Telephone: +44-1865-220325 Fax: +44-1865-740409
Received: July 26, 2014
Peer-review started: July 27, 2014
First decision: September 16, 2014
Revised: September 29, 2014
Accepted: October 28, 2014
Article in press: October 29, 2014
Published online: February 16, 2015
Processing time: 193 Days and 18.1 Hours
Peer-review started: July 27, 2014
First decision: September 16, 2014
Revised: September 29, 2014
Accepted: October 28, 2014
Article in press: October 29, 2014
Published online: February 16, 2015
Processing time: 193 Days and 18.1 Hours
Core Tip
Core tip: Coronary artery disease remains the leading cause of death worldwide. There is increasing evidence to suggest that the use of invasive coronary angiography alone may not reliably identify all lesions associated with haemodynamic compromise. Technological advances have enabled the measurement of a number of coronary physiological indices which when incorporated into routine practice are associated with improved outcomes, reduced risks and greater economy. This review will discuss current concepts relevant to coronary physiology assessment, its role in the management of both stable and acute patients and future applications.