Gollol Raju NS, Joshi D, Daggubati R, Movahed A. Contrast induced neurotoxicity following coronary angiogram with Iohexol in an end stage renal disease patient. World J Clin Cases 2015; 3(11): 942-945 [PMID: 26601097 DOI: 10.12998/wjcc.v3.i11.942]
Corresponding Author of This Article
Assad Movahed, MD, FACC, FACP, Department of Cardiovascular Sciences, East Carolina University-Brody School of Medicine, 115 Heart Drive, Greenville, NC 27834, United States. movaheda@ecu.edu
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Narasimha Swamy Gollol Raju, Department of Internal Medicine, East Carolina University-Brody School of Medicine, Greenville, NC 27834, United States
Deepak Joshi, Ramesh Daggubati, Assad Movahed, Department of Cardiovascular Sciences, East Carolina University-Brody School of Medicine, Greenville, NC 27834, United States
Author contributions: All authors contributed to the acquisition of information, writing and revision of this case report.
Institutional review board statement: This case report was exempt from the Institutional Review Board standards at East Carolina University.
Informed consent statement: The patient involved in this study gave informed consent authorizing use and disclosure of protected health information.
Conflict-of-interest statement: All the authors have no conflicts of interests to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Assad Movahed, MD, FACC, FACP, Department of Cardiovascular Sciences, East Carolina University-Brody School of Medicine, 115 Heart Drive, Greenville, NC 27834, United States. movaheda@ecu.edu
Telephone: +1-252-7444400 Fax: +1-252-7447725
Received: May 6, 2015 Peer-review started: May 8, 2015 First decision: July 10, 2015 Revised: July 23, 2015 Accepted: September 7, 2015 Article in press: September 8, 2015 Published online: November 16, 2015 Processing time: 188 Days and 17.1 Hours
Core Tip
Core tip: Contrast induced neurotoxicity following coronary angiogram is very rare. Interventionalists should be aware of this rare complication especially in patients with end stage renal disease (ESRD). Iodinated contrast media can be effectively removed from the blood by dialysis. Hemodialysis is a better modality for rapid removal of contrast agent compared to peritoneal dialysis. Hemodialysis should be considered in life-threatening adverse reactions when supportive care alone is not sufficient. More studies are needed to further delineate the role and timing of hemodialysis following coronary angiogram and the optimal dosage of contrast media in ESRD patients to prevent this infrequent but potentially life threatening adverse reaction.
