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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 16, 2014; 2(9): 469-473
Published online Sep 16, 2014. doi: 10.12998/wjcc.v2.i9.469
Published online Sep 16, 2014. doi: 10.12998/wjcc.v2.i9.469
Pneumatosis cystoides intestinalis associated with toxic epidermal necrolysis: A case report
Si-Yuan Yao, Departments of Surgery, Kobe City Medical Center General Hospital, Chuo-ku, Kobe 650-0047, Japan
Ryutaro Seo, Kazuo Yamazaki, Departments of Anesthesiology, Kobe City Medical Center General Hospital, Chuo-ku, Kobe 650-0047, Japan
Tohru Nagano, Departments of Dermatology, Kobe City Medical Center General Hospital, Chuo-ku, Kobe 650-0047, Japan
Author contributions: Yao SY, Seo R, Nagano T and Yamazaki K contributed to the manuscript writing and revision.
Correspondence to: Si-Yuan Yao, MD, Departments of Surgery, Kobe City Medical Center General Hospital, 2-1-1, Minatojima-Minamimachi, Chuo-ku, Kobe 650-0047, Japan. siyuan@kobe-nishishimin-hospi.jp
Telephone: +81-78-3024321 Fax: +81-78-3027537
Received: April 30, 2014
Revised: June 3, 2014
Accepted: June 27, 2014
Published online: September 16, 2014
Revised: June 3, 2014
Accepted: June 27, 2014
Published online: September 16, 2014
Core Tip
Core tip: Toxic epidermal necrolysis is a severe adverse drug reaction, which affects skin and mucosa of whole body. However, intestinal involvement is rare documented. We report the case of a 55-year-old man with toxic epidermal necrolysis caused by phenobarbital. He was diagnosed with pneumatosis cystoides intestinalis during the clinical course. Although septic shock was accompanied, conservative treatment was effective. To our knowledge, this article describes the first patient presenting with pneumatosis cystoides intestinalis associated with toxic epidermal necrolysis.