Disseminated infection due to Mycobacterium bovis after intravesical BCG instillation

doi:10.12998/wjcc.v2.i7.301

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Jul 16, 2014 (publication date) through May 1, 2024

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Jul 16, 2014; 2(7): 301-303
Published online Jul 16, 2014. doi: 10.12998/wjcc.v2.i7.301

Disseminated infection due to Mycobacterium bovis after intravesical BCG instillation

Sara Marquez-Batalla, Esther Fraile-Villarejo, Moncef Belhassen-García, Nieves Gutierrez-Zubiaurre, Miguel Cordero-Sánchez

Sara Marquez-Batalla, Esther Fraile-Villarejo, Servicio de Medicina Interna (CAUSA), IBSAL, Universidad de Salamanca, 37007 Salamanca, Spain

Moncef Belhassen-García, Miguel Cordero-Sánchez, Servicio de Medicina Interna, Seccion de Enfermedades Infecciosas, Complejo Asistencial Universitario de Salamanca (CAUSA), Instituto de investigacion Biomedica de Salamanca (IBSAL), Universidad de Salamanca, 37007 Salamanca, Spain

Nieves Gutierrez-Zubiaurre, Servicio de Microbiologia, (CAUSA), CIETUS, IBSAL, 37007 Salamanca, Spain

Author contributions: Marquez-Batalla S and Fraile-Villarejo E collected the patients clinical data; Gutierrez-Zubiaurre N performed the microbiological analyses; Marquez-Batalla S, Cordero-Sanchez M and Belhassen-Garcia M designed the report and wrote the paper.

Correspondence to: Moncef Belhassen-García, MD, PhD, Servicio de Medicina Interna, Seccion de Enfermedades Infecciosas, Complejo Asistencial Universitario de Salamanca (CAUSA), Instituto de investigacion Biomedica de Salamanca (IBSAL), Universidad de Salamanca, Paseo San Vicente 58-182, 37007 Salamanca, Spain. mbelhassen@hotmail.com

Telephone: +34-923-291306 Fax: +34-923-291131

Received: February 22, 2014
Revised: April 19, 2014
Accepted: April 25, 2014
Published online: July 16, 2014

Core Tip

Core tip: Intravesical instillation of bacillus Calmette-Guerin (BCG) is a therapeutic option in bladder cancer. Multi-system effects are a rare complication of this procedure, and certain aspects concerning its diagnosis and treatment are unclear. We report the case of a patient who developed effects on multiple organs after intravesical BCG instillations, and we review current knowledge concerning the diagnosis and management of BCG infection.