Case Report
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World J Clin Cases. Jul 16, 2014; 2(7): 284-288
Published online Jul 16, 2014. doi: 10.12998/wjcc.v2.i7.284
Verrucous carcinoma of the esophagus: A case report and literature review
Chintan Ramani, Neil Shah, Ramasamy Swami Nathan
Chintan Ramani, Neil Shah, Ramasamy Swami Nathan, Department of internal medicine, Hackensack UMC mountainside, Montclair, NJ 07042, United States
Author contributions: Nathan RS performed the endoscopy and diagnosed the case; Ramani C with Shah N and Nathan RS did the literature search and Ramani C wrote a report.
Correspondence to: Ramasamy Swami Nathan, MD, Academic Chief Gastroenterology, Department of internal medicine, Hackensack UMC mountainside, 1 Bay Ave, Montclair, NJ 07042, United States. chintan.ramani@mountainsidehosp.com
Telephone: +1-973-2398372 Fax: +1-973-2398403
Received: October 28, 2013
Revised: March 23, 2014
Accepted: May 19, 2014
Published online: July 16, 2014
Processing time: 37 Days and 10.9 Hours
Core Tip

Core tip: A verrucous carcinoma is a slow growing, well differentiated, rare form of squamous carcinoma variant. It is associated with chronic, local disease process and it invades locally. On endoscopy (EGD), it appears as an exophytic irregular warty projecting mass, and it is very difficult to diagnose by superficial biopsy due to non specific superficial histological findings. So it requires high index of suspicion and deep biopsy with EGD or endoscopic ultrasonography (EUS). It projects as hypoechoic mucosal thickening on EUS. Early stages of cancers are treated surgically. Advanced cases can be referred for esophageal stent placement for palliation and chemo radiation. It has high morbidity and mortality and requires long term follow up for accurate numbers regarding to the treatment and the follow up.