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World J Clin Cases. Jul 16, 2014; 2(7): 253-256
Published online Jul 16, 2014. doi: 10.12998/wjcc.v2.i7.253
Critical review of topical management of oral hairy leukoplakia
Cláudia B Brasileiro, Mauro Henrique NG Abreu, Ricardo A Mesquita
Cláudia B Brasileiro, Ricardo A Mesquita, Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Pampulha, 31270-901, Belo Horizonte/MG, Brazil
Mauro Henrique NG Abreu, Department of Community and Preventive Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Pampulha, 31270-901, Belo Horizonte/MG, Brazil
Author contributions: Mesquita RA and Abreu MHNG were responsible for the concept and review of the manuscript; Brasileiro CB performed research and wrote the manuscript.
Correspondence to: Ricardo A Mesquita, PhD, Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, sala 3202-D, Av. Antônio Carlos, 6627, Pampulha, 31270-901, Belo Horizonte/MG, Brazil. ramesquita@ufmg.br
Telephone: +55-31-34092499 Fax: +55-31-34092430
Received: January 28, 2014
Revised: April 2, 2014
Accepted: May 16, 2014
Published online: July 16, 2014
Processing time: 173 Days and 11.4 Hours
Core Tip

Core tip: This literature review was performed to assess the evidence for topical treatments for oral hairy leukoplakia (OHL). Although highly active antiretroviral therapy has reduced oral lesions associated with human immunodeficiency virus, prevalence studies revealed that OHL is still observed in patients with HIV infections. Knowledge about appropriate management of this condition is relevant, specifically regarding topical treatments that are less invasive, low-cost, easy to apply and free of systemic adverse effects.