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World J Clin Cases. Dec 16, 2014; 2(12): 888-892
Published online Dec 16, 2014. doi: 10.12998/wjcc.v2.i12.888
Published online Dec 16, 2014. doi: 10.12998/wjcc.v2.i12.888
Appendiceal Crohn’s disease clinically presenting as acute appendicitis
Hulin Han, Hyunsung Kim, Abdul Rehman, Se Min Jang, Seung Sam Paik, Department of Pathology, College of Medicine, Hanyang University, Seoul 133-792, South Korea
Author contributions: Kim H and Rehman A contributed to acquisition of data, the literature search and improved manuscript’s English; Jang SM revised the manuscript critically for important intellectual content; Han H and Paik SS designed and wrote this paper.
Correspondence to: Seung Sam Paik, MD, Department of Pathology, College of Medicine, Hanyang University, 222 Wangsimri-ro, Sungdong-ku, Seoul 133-792, South Korea. sspaik@hanyang.ac.kr
Telephone: +82-2-22908252 Fax: +82-2-22967502
Received: July 24, 2014
Revised: August 19, 2014
Accepted: October 28, 2014
Published online: December 16, 2014
Revised: August 19, 2014
Accepted: October 28, 2014
Published online: December 16, 2014
Core Tip
Core tip: Appendiceal Crohn’s disease (CD) is relatively rare and is indistinguishable from acute appendicitis. Appendiceal CD shows a favorable clinical outcome with a low recurrence rate. The differential diagnosis includes intestinal tuberculosis, foreign body reaction, diverticulitis of the appendix, sarcoidosis, actinomycosis, and Yersinia infection. Atypical and protracted clinical course, unusual gross features of the appendix and the characteristic histologic features are a clue in the diagnosis of appendiceal CD.