Letter to the Editor
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 16, 2025; 13(8): 98379
Published online Mar 16, 2025. doi: 10.12998/wjcc.v13.i8.98379
Association of interleukin-6 with acute lung injury risk and disease severity in sepsis
Imshaal Musharaf, Abdulqadir J Nashwan
Imshaal Musharaf, Department of Medicine, Jinnah Sindh Medical University, Karachi 75510, Pakistan
Abdulqadir J Nashwan, Department of Nursing and Midwifery Research, Hamad Medical Corporation, Doha 3050, Qatar
Author contributions: Musharaf I and Nashwan AJ writing the draft and critically reviewing the literature.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Abdulqadir J Nashwan, MSc, PhD, Research Scientist, Department of Nursing and Midwifery Research, Hamad Medical Corporation, Rayyan Road, Doha 3050, Qatar. anashwan@hamad.qa
Received: June 25, 2024
Revised: November 4, 2024
Accepted: November 26, 2024
Published online: March 16, 2025
Processing time: 162 Days and 0.1 Hours
Core Tip

Core Tip: The study explores the association of interleukin-6 levels with the risk of developing acute lung injury and multiple organ dysfunction syndrome in critically ill sepsis patients. It underscores its potential as a valuable biomarker for prognosis and guiding treatment in intensive care settings. However, limitations like an observational study design, a limited sample size, a single center involvement, single-time-point measurement, and no control group should be considered in further research.