Retrospective Study
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World J Clin Cases. Mar 16, 2025; 13(8): 97887
Published online Mar 16, 2025. doi: 10.12998/wjcc.v13.i8.97887
Chyle leak following root of mesentery dissection in pancreaticoduodenectomy with inferior infracolic superior mesenteric artery first approach
Prabir Maharjan, Sujan Regmee, Spandan D Adhikari, Rabin Pahari, Roshan Ghimire, Dhiresh K Maharjan, Suman K Shrestha, Prabin B Thapa
Prabir Maharjan, Sujan Regmee, Spandan D Adhikari, Rabin Pahari, Roshan Ghimire, Dhiresh K Maharjan, Suman K Shrestha, Prabin B Thapa, Department of Gastrointestinal and General Surgery, Kathmandu Medical College and Teaching Hospital, Kathmandu 44600, Nepal
Author contributions: Maharjan P, Regmee S, Adhikari SD, Pahari R, Ghimire R, Maharjan DK, Shrestha SK, and Thapa PB contributed to the conceptualization of the study; Maharjan P and Regmee S contributed to the data curation; Maharjan P, Adhikari SD, and Pahari R contributed to the formal analysis; Maharjan P, Regmee S, Ghimire R, Maharjan DK, and Thapa PB performed the methodology; Maharjan P, Regmee S, and Shrestha SK contributed to the project administration; Maharjan P and Ghimire R contributed to the resourcing; Maharjan P and Regmee S provided software expertise; Maharjan P, Ghimire R, Maharjan DK, and Thapa PB contributed to the supervision of the study; Maharjan P, Regmee S, Ghimire R, Maharjan DK, and Thapa PB contributed to the writing, review, and editing of the manuscript; and all authors read and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Kathmandu Medical College Institutional Review Committee, approval Ref: 25032024/02.
Informed consent statement: All study participants, or their legal guardians, provided informed consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Participants gave informed consent for data sharing. No additional data available apart from the mentioned data.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Prabir Maharjan, Department of Gastrointestinal and General Surgery, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu 44600, Nepal. prabirstx493@kmc.edu.np
Received: June 12, 2024
Revised: November 2, 2024
Accepted: November 20, 2024
Published online: March 16, 2025
Processing time: 174 Days and 22.5 Hours
Core Tip

Core Tip: Pancreatoduodenectomy is invariably discussed in terms of its weightage of surgery and frequent complications like post-operative pancreatic fistula, post-pancreatectomy hemorrhage, and delayed gastric emptying. However, chyle leak is rarely discussed. This article is a testament to the outcomes of the root of mesentery dissection with the virtue of achieving complete oncological resection. This article discusses the incidence, clinical impact, and risk factors of chyle leak following the root of mesentery dissection in pancreaticoduodenectomy, emphasizing effective management without re-exploration but utilizing total parenteral nutrition and dietary restrictions without adverse effect on the outcome.