Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 16, 2025; 13(8): 100889
Published online Mar 16, 2025. doi: 10.12998/wjcc.v13.i8.100889
Transient extreme insulin resistance in a critically ill patient: A case report
Xiu-Yu Wei, Hsiu-Nien Shen
Xiu-Yu Wei, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung 407, Taiwan
Hsiu-Nien Shen, Department of Intensive Care Medicine, Chi Mei Medical Center, Tainan 710, Taiwan
Author contributions: Wei XY collected the data and wrote the manuscript; Shen HN revised the manuscript; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hsiu-Nien Shen, MD, PhD, Attending Doctor, Department of Intensive Care Medicine, Chi Mei Medical Center, No. 901 Zhonghua Road, Yongkang District, Tainan 710, Taiwan. hsiunian@gmail.com
Received: August 29, 2024
Revised: October 29, 2024
Accepted: November 22, 2024
Published online: March 16, 2025
Processing time: 97 Days and 0.4 Hours
Core Tip

Core Tip: The occurrence of transient extreme insulin resistance requiring exceptional high-dose insulin is rare, which is typically transient. Clinicians should be aware of the phenomenon and cautious to avoid hypoglycemia and fluid overload during the steep titration of high-dose insulin infusion.