Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 16, 2025; 13(8): 100028
Published online Mar 16, 2025. doi: 10.12998/wjcc.v13.i8.100028
Unusual ovarian hyperstimulation syndrome presentation: Pleural effusion without ascites. A case report
Íngrid Solsona, Sara Peralta, Yasmina Barral, Francisco Fàbregues, Pepita Giménez-Bonafé
Íngrid Solsona, Department of Physiological Sciences, Physiology Unit, Faculty of Medicine and Health Sciences, Bellvitge Campus, Universitat de Barcelona, IDIBELL, Barcelona 08907, Catalonia, Spain
Sara Peralta, Yasmina Barral, Francisco Fàbregues, Institut Clinic of Gynecology, Obstetrics and Neonatology, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Faculty of Medicine, University of Barcelona, Barcelona 08036, Catalonia, Spain
Pepita Giménez-Bonafé, Department of Physiological Sciences, Faculty of Medicine and Health Sciences, Bellvitge Campus, Universitat de Barcelona, IDIBELL, L'Hospitalet de Llobregat 08907, Barcelona, Spain
Author contributions: Solsona I and Peralta S collected the clinical information of the patient; Solsona I and Fàbregues F wrote the manuscript; Peralta S and Barral Y added information to the manuscript; Solsona I and Barral Y prepared the figures; Solsona I, Peralta S, Barral Y, Fàbregues F and Giménez-Bonafé P reviewed the manuscript; Giménez-Bonafé P supervised the data collection, organized the manuscript, corrected the English, and reviewed the final version of the manuscript.
Informed consent statement: The patient has given her consent for both the photos and her clinical information to be used anonymously for the publication of her case study.
Conflict-of-interest statement: The authors declare there is no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Pepita Giménez-Bonafé, BSc, MSc, PhD, Professor, Senior Research Fellow, Department of Physiological Sciences, Faculty of Medicine and Health Sciences, Bellvitge Campus, Universitat de Barcelona, IDIBELL, Carrer Feixa Llarga, s/n, L'Hospitalet de Llobregat 08907, Barcelona, Spain. pgimenez@ub.edu
Received: August 9, 2024
Revised: September 24, 2024
Accepted: October 16, 2024
Published online: March 16, 2025
Processing time: 116 Days and 17.8 Hours
Core Tip

Core Tip: With the increasing use of assisted reproductive technologies, ovarian hyperstimulation syndrome (OHSS) should be a topic of continued research, and it is crucial to develop systematic guidelines for prevention, diagnosis, and management. The present case underscores the severe nature of OHSS and its potential complications, which can include respiratory distress and pleural effusion, as well as impact on the cardiac function. Furthermore, it highlights an atypical presentation of OHSS in a patient without identifiable risk factors, suggesting a need for reconsideration of both the criteria defining at-risk patients, and consequently identifying individuals who would benefit from preventive measures.