Spectrum of venous thromboembolism in adult patients with ulcerative colitis in Pakistan: A single center retrospective study

doi:10.12998/wjcc.v13.i6.99648

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Feb 26, 2025 (publication date) through Dec 26, 2024

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Clin Cases. Feb 26, 2025; 13(6): 99648
Published online Feb 26, 2025. doi: 10.12998/wjcc.v13.i6.99648

Spectrum of venous thromboembolism in adult patients with ulcerative colitis in Pakistan: A single center retrospective study

Masood Muhammad Karim, Hafsa Shaikh, Faisal Wasim Ismail

Masood Muhammad Karim, Faisal Wasim Ismail, Department of Medicine, The Aga Khan University Hospital, Karachi 74800, Pakistan

Hafsa Shaikh, Department of General Surgery, The Aga Khan University Hospital, Karachi 74800, Pakistan

Author contributions: Karim MM and Shaikh H were responsible for data collection and manuscript writing; Ismail FW was responsible for study conception and manuscript formatting; all the authors have read and approved the final version of the manuscript.

Institutional review board statement: This study was approved by the Institutional Review Board of Aga Khan University, Karachi.

Informed consent statement: The need for informed consent was waived due to the retrospective nature of the study.

Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.

Data sharing statement: No additional data available.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Faisal Wasim Ismail, FACG, FACP, FCPS, MBBS, Associate Professor, Department of Medicine, The Aga Khan University Hospital, National Stadium Road, Karachi 74800, Pakistan. faisal.ismail@aku.edu

Received: July 26, 2024
Revised: August 17, 2024
Accepted: September 6, 2024
Published online: February 26, 2025
Processing time: 121 Days and 14 Hours

Core Tip

Core Tip: This study highlights the paucity of data available on prevalence of venous thromboembolism in patients with ulcerative colitis (UC) in a low to middle income setting. Although previous studies have shown that patients with acute flare of UC were likely to develop thromboembolism, our data suggests otherwise. Furthermore, this study opens up a new question regarding whether UC is associated with thrombophilic conditions such as protein C deficiency.