Mucocutaneous manifestation mimicking vasculitis in chronic hepatitis B: A case report

doi:10.12998/wjcc.v13.i29.109516

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World Journal of Clinical Cases

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Case Report

World J Clin Cases. Oct 16, 2025; 13(29): 109516
Published online Oct 16, 2025. doi: 10.12998/wjcc.v13.i29.109516

Mucocutaneous manifestation mimicking vasculitis in chronic hepatitis B: A case report

Jin Won Kim, Shin Young Park, Nah Ihm Kim, Sung Kyu Choi, Jae Hyun Yoon

Jin Won Kim, Shin Young Park, Sung Kyu Choi, Jae Hyun Yoon, Department of Gastroenterology and Hepatology, Chonnam National University Hospital and Medical School, Gwangju 61469, South Korea

Nah Ihm Kim, Department of Pathology, Chonnam National University Hospital, Gwangju 61469, South Korea

Author contributions: Yoon JH contributed to conceptualization, data curation, funding acquisition, project administration, resources, visualization; Park SY contributed to data curation, investigation, writing – original draft; Choi SK contributed to project administration, visualization; Kim NI contributed to resources; Kim JW contributed to writing – original draft, writing – review & editing.

Supported by Chonnam National University Hospital Biomedical Research Institute, No. BCRE23215.

Informed consent statement: Written informed consent was obtained from the patient for publication of this case report and any accompanying images.

Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.

CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Jae Hyun Yoon, MD, PhD, Department of Gastroenterology and Hepatology, Chonnam National University Hospital and Medical School, Je-bong ro 42, Dong Gu, Gwangju 61469, South Korea. zenmake14@gmail.com

Received: May 19, 2025
Revised: June 11, 2025
Accepted: July 22, 2025
Published online: October 16, 2025
Processing time: 104 Days and 3.8 Hours

Core Tip

Core Tip: Our case report highlight that extrahepatic manifestations affecting the skin and mucosa can occur in chronic hepatitis B patients, even during nucleotide analogue treatment, and may be effectively managed with systemic steroids, likely targeting immune complex-mediated inflammation.