Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 16, 2025; 13(14): 102791
Published online May 16, 2025. doi: 10.12998/wjcc.v13.i14.102791
Lymphogranuloma venereum proctosigmoiditis misdiagnosed as inflammatory bowel disease: A case report
Kaline Maya Khoury, Ahmad Jradi, Karam Karam, Elias Fiani
Kaline Maya Khoury, Ahmad Jradi, Department of Internal Medicine, University of Balamand, Beirut 100, Beyrouth, Lebanon
Karam Karam, Department of Gastroenterology, University of Balamand, Beirut 100, Beyrouth, Lebanon
Elias Fiani, Department of Gastroenterology and Hepatology, University of Balamand, Beirut 100, Beyrouth, Lebanon
Co-first authors: Kaline Maya Khoury and Ahmad Jradi.
Co-corresponding authors: Karam Karam and Elias Fiani.
Author contributions: Maya KK and Ahmad J performed the literature review with data curation, investigation and writing original draft; Karam K and Fiani E performed editing of the first draft, investigation and supervising the work of first co-authors.
Informed consent statement: A signed written informed consent was obtained from the patient prior to writing the manuscript.
Conflict-of-interest statement: The authors declare no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Elias Fiani, Department of Gastroenterology and Hepatology, University of Balamand, Dekweneh, Beirut 100, Beyrouth, Lebanon. elias.fiani@hotmail.com
Received: October 29, 2024
Revised: December 20, 2024
Accepted: January 7, 2025
Published online: May 16, 2025
Processing time: 78 Days and 15.4 Hours
Core Tip

Core Tip: Lymphogranuloma venereum (LGV) should be considered as one of the differential diagnosis when confronting a patient with rectal symptoms to avoid misdiagnosis and needless treatments. Differentiating between LGV and inflammatory bowel disease can be challenging due to their similarity in clinical, endoscopic, and histopathological features especially in patients whom sexual history is not known. Our case illustrates the importance of sexual history in our diagnostic approach and the urge for clinicians to increase awareness of LGV among high risk populations.