Randomized Controlled Trial
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 16, 2025; 13(14): 102534
Published online May 16, 2025. doi: 10.12998/wjcc.v13.i14.102534
Role of disturbance coefficient in monitoring and treatment of cerebral edema in patients with cerebral hemorrhage
Wen-Wen Gao, Xiao-Bing Jiang, Peng Chen, Liang Zhang, Lei Yang, Zhi-Hai Yuan, Yao Wei, Xiao-Qiang Li, Xiao-Lu Tang, Feng-Lu Wang, Hao Wu, Hai-Kang Zhao
Wen-Wen Gao, Xiao-Bing Jiang, Peng Chen, Liang Zhang, Lei Yang, Zhi-Hai Yuan, Yao Wei, Xiao-Qiang Li, Xiao-Lu Tang, Feng-Lu Wang, Hao Wu, Hai-Kang Zhao, Department of Neurosurgery, The Second Affiliated Hospital of Xi’an Medical University, Xi’an 710038, Shaanxi Province, China
Hao Wu, Department of Neurosurgery, Xi’an Medical University, Xi’an 710021, Shaanxi Province, China
Co-first authors: Wen-Wen Gao and Xiao-Bing Jiang.
Co-corresponding authors: Hao Wu and Hai-Kang Zhao.
Author contributions: Gao WW and Wu H designed the work and performed the analysis; Wang FL, Zhang L, and Wu H interpreted the data; Chen P, Wei Y, Yuan ZH, Jiang XB, Yang L, Tang XL, and Li XQ created the new software used in this research; Zhao HK and Wu H drafted and revised the manuscript; all authors have read and approved the final manuscript.
Supported by the Shaanxi Provincial Key Research and Development Plan Project, No. 2020ZDLSF01-02.
Institutional review board statement: This study involved human subjects and was reviewed and approved by the Ethics Review Committee of the Second Affiliated Hospital of Xi’an Medical University (approval No. 2020 LP01).
Clinical trial registration statement: Public title: Establishment and application of a new system for diagnosis and treatment of cerebral hemorrhage based on multimodal monitoring of domestic innovative medical equipment (No. ChiCTR2000033829).
Informed consent statement: Signed informed consent was obtained from all the participants.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hai-Kang Zhao, MD, PhD, Chief Physician, Department of Neurosurgery, The Second Affiliated Hospital of Xi’an Medical University, No. 167 Fangdong Street, Baqiao District, Xi’an 710038, Shaanxi Province, China. xmu2neurosurgery@163.com
Received: October 22, 2024
Revised: December 15, 2024
Accepted: January 3, 2025
Published online: May 16, 2025
Processing time: 86 Days and 2.9 Hours
Core Tip

Core Tip: The disturbance coefficient for non-invasive dynamic monitoring of cerebral edema possesses certain guiding significance for the treatment of cerebral edema, which can not only reduce the total dosage of mannitol and the incidence of complications, but also shorten hospital stays, reduce the total cost of hospitalization, and improve the overall prognosis rate of patients. Therefore, it can be used as a new method of clinical non-invasive adjuvant therapy.