Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 6, 2025; 13(10): 101935
Published online Apr 6, 2025. doi: 10.12998/wjcc.v13.i10.101935
Homozygous phytosterolemia and a literature review: A case report
Chun-Xin Jiang, Guang Yang, Lian-Ping Shi, Peng-Yu Su
Chun-Xin Jiang, Guang Yang, Lian-Ping Shi, Peng-Yu Su, Department of Cardiovascular, North China University of Science and Technology Affiliated Hospital, Tangshan 063000, Hebei Province, China
Co-first authors: Chun-Xin Jiang and Guang Yang.
Author contributions: Su PY designed the research study; Jiang CX and Shi LP performed the research; Jiang CX and Yang G analyzed the data and wrote the manuscript. Jiang CX and Yang G contributed equally to this work as co-first authors.
Supported by Natural Science Foundation of Heibei Province, No. H2020209160.
Informed consent statement: All study participants and their legal guardians provided informed written consent prior to enrolment in the study.
Conflict-of-interest statement: All the authors report having no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Peng-Yu Su, MD, PhD, Department of Cardiovascular, North China University of Science and Technology Affiliated Hospital, No. 73 South Construction Road, Lubei District, Tangshan 063000, Hebei Province, China. yezi9725@sina.com
Received: October 1, 2024
Revised: October 31, 2024
Accepted: December 3, 2024
Published online: April 6, 2025
Processing time: 78 Days and 9.6 Hours
Core Tip

Core Tip: We have reported a rare homozygous phytosterolemia. We followed up the patient and found that dietary regulation can play a role in lowering blood lipids, and lipid-lowering drugs can be avoided if the diet is well controlled. Second, ezetimibe can reduce plant steroidemia. Most of the parents of homozygous plant steroidemia are close relatives. In this case, the parents of the patient are not close relatives. We will also follow up the patient's family members.