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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 16, 2024; 12(5): 966-972
Published online Feb 16, 2024. doi: 10.12998/wjcc.v12.i5.966
Published online Feb 16, 2024. doi: 10.12998/wjcc.v12.i5.966
Clinical significance of platelet mononuclear cell aggregates in patients with sepsis and acute respiratory distress syndrome
Chong-Min Huang, Department of Intensive Medicine, The Second People's Hospital of Haining City, Haining 314419, Zhejiang Province, China
Juan-Juan Li, Wei-Ke Wei, Department of Integrated Traditional Chinese and Western Medicine, Qingyang Hospital, Hangzhou 310023, Zhejiang Province, China
Author contributions: Huang CM performed the study; Li JJ analyzed the data; Wei WK designed the research and wrote the manuscript; All authors have read and approve the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of the Second People's Hospital of Haining City.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chong-Min Huang, MD, Doctor, Department of Intensive Medicine, The Second People's Hospital of Haining City, No. 85 Guoque Road, Maqiao Street, Haining 314419, Zhejiang Province, China. 15325307291@163.com
Received: November 16, 2023
Peer-review started: November 16, 2023
First decision: December 26, 2023
Revised: December 30, 2023
Accepted: January 24, 2024
Article in press: January 24, 2024
Published online: February 16, 2024
Processing time: 75 Days and 17.6 Hours
Peer-review started: November 16, 2023
First decision: December 26, 2023
Revised: December 30, 2023
Accepted: January 24, 2024
Article in press: January 24, 2024
Published online: February 16, 2024
Processing time: 75 Days and 17.6 Hours
Core Tip
Core Tip: Our research aimed to investigate the expression of platelet mononuclear cell aggregates (PMAs) in the serum of patients with sepsis complicated by acute respiratory distress syndrome (ARDS) and its clinical significance. The results indicate that the serum levels of PMAs significantly increase in patients with sepsis and ARDS. Therefore, serum PMAs have the potential to become a new biomarker for clinically diagnosing sepsis complicated by ARDS.