Merits and demerits of administering esketamine in preventing postpartum depression following cesarean section

doi:10.12998/wjcc.v12.i36.6883

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Dec 26, 2024 (publication date) through Nov 1, 2024

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Dec 26, 2024; 12(36): 6883-6886
Published online Dec 26, 2024. doi: 10.12998/wjcc.v12.i36.6883

Merits and demerits of administering esketamine in preventing postpartum depression following cesarean section

Takahiko Nagamine

Takahiko Nagamine, Department of Psychiatric Internal Medicine, Sunlight Brain Research Center, Hofu 7470066, Yamaguchi, Japan

Author contributions: Nagamine T conceptualized the editorial and was solely responsible for the investigation, writing of the original draft, and all subsequent review and editing activities.

Conflict-of-interest statement: All authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Takahiko Nagamine, MD, PhD, Chief Doctor, Department of Psychiatric Internal Medicine, Sunlight Brain Research Center, 4-13-18 Jiyugaoka, Hofu, Yamaguchi, Hofu 7470066, Yamaguchi, Japan. anagamine@yahoo.co.jp

Received: August 14, 2024
Revised: September 1, 2024
Accepted: September 10, 2024
Published online: December 26, 2024
Processing time: 77 Days and 23.4 Hours

Core Tip

Core Tip: Emergency cesarean section is a risk factor for postpartum depression. Esketamine is effective in preventing postpartum depression after cesarean section. However, esketamine carries a risk of inducing psychotic symptoms, such as hallucinations and dissociation. The use of esketamine during cesarean section should be restricted to appropriate patients, taking into account its benefits and drawbacks.