Letter to the Editor
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 26, 2024; 12(33): 6655-6659
Published online Nov 26, 2024. doi: 10.12998/wjcc.v12.i33.6655
Targeting nuclear factor erythroid 2-related factor 2-regulated ferroptosis to treat nervous system diseases
Ye-Qi Huang, Zheng-Wei Huang, Xue-Juan Zhang
Ye-Qi Huang, Zheng-Wei Huang, Xue-Juan Zhang, College of Pharmacy, Jinan University, Guangzhou 510006, Guangdong Province, China
Co-corresponding authors: Zheng-Wei Huang and Xue-Juan Zhang.
Author contributions: Huang YQ was responsible for writing original draft preparation, review, and editing; Huang ZW was responsible for original draft preparation, conceptualization supervision, and funding acquisition; Zhang XJ was responsible for supervision and funding acquisition; all of the authors read and approved the final version of the manuscript to be published.
Supported by The Guangdong Basic and Applied Basic Research Foundation, China, No. 2024A1515011236.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zheng-Wei Huang, PharmD, Teacher, College of Pharmacy, Jinan University, No. 855 East Xingye Dadao, Panyu District, Guangzhou 510006, Guangdong Province, China. huangzhengw@jnu.edu.cn
Received: May 22, 2024
Revised: September 11, 2024
Accepted: September 19, 2024
Published online: November 26, 2024
Processing time: 127 Days and 17.8 Hours
Core Tip

Core Tip: Based on the original paper, this study highlights two primary points: Bibliometric methodologies and future perspectives for nuclear factor erythroid 2-related factor 2 (NRF2) research. We emphasize the need for broader literature databases and diversified analysis methods in bibliometric research. Additionally, we highlight the importance of NRF2 modulation in regulating ferroptosis for treating nervous system diseases and discuss how nanoparticle drug delivery systems may overcome challenges associated with NRF2-related drugs.