Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2024; 12(31): 6493-6499
Published online Nov 6, 2024. doi: 10.12998/wjcc.v12.i31.6493
Managing Vogt–Koyanagi–Harada disease during pregnancy with steroid pulse therapy: A case report
Kyouhei Ueyama, Toshiyuki Kakinuma, Keisuke Mori, Ayumi Hayashi, Kaoru Kakinuma, Rora Okamoto, Ayaka Kaneko, Kaoru Yanagida, Nobuhiro Takeshima, Michitaka Ohwada
Kyouhei Ueyama, Toshiyuki Kakinuma, Kaoru Kakinuma, Rora Okamoto, Ayaka Kaneko, Kaoru Yanagida, Nobuhiro Takeshima, Michitaka Ohwada, Department of Obstetrics and Gynecology, International University of Health and Welfare Hospital, Tochigi 329-2763, Nasushiobara, Japan
Keisuke Mori, Ayumi Hayashi, Department of Ophthalmology, International University of Health and Welfare Hospital, Tochigi 327-2763, Japan
Author contributions: Ueyama K and Kakinuma T designed the research study; All authors performed the research; Ueyama K and Kakinuma T analyzed the data and wrote the manuscript; All authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Toshiyuki Kakinuma, MD, PhD, Professor, Department of Obstetrics and Gynecology, International University of Health and Welfare Hospital, 537-3, Iguchi, Tochigi 329-2763, Nasushiobara, Japan. tokakinuma@gmail.com
Received: May 9, 2024
Revised: August 22, 2024
Accepted: August 28, 2024
Published online: November 6, 2024
Processing time: 124 Days and 18.7 Hours
Core Tip

Core Tip: Generally, high-dose steroid administration is the initial treatment for Vogt–Koyanagi–Harada disease (VKH). However, administering large doses of steroids to pregnant women requires careful treatment, considering their effects on the mother and fetus. We report a case in which steroid pulse therapy was administered to a patient who developed VKH during late pregnancy, and multidisciplinary management led to normal delivery. When treating VKH that develops during pregnancy, multidisciplinary management is considered necessary, with close collaboration not only with ophthalmologists, but also internal medicine and neonatologists.