Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2024; 12(31): 6436-6440
Published online Nov 6, 2024. doi: 10.12998/wjcc.v12.i31.6436
Molecular diagnostic approaches in detecting rearranged during transfection oncogene mutations in multiple endocrine neoplasia type 2
Sambasivam Gopinath, Velmurugan Ramaiyan
Sambasivam Gopinath, Velmurugan Ramaiyan, Department of Pharmacy, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences, Chennai 602105, India
Author contributions: Gopinath S designed the overall concept and outline of the manuscript; Velmurugan R contributed to the discussion and design of the manuscript; Gopinath S and Velmurugan R contributed to the writing and editing of the manuscript, and review of the literature; all authors have read and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Velmurugan Ramaiyan, PhD, Professor, Department of Pharmacy, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences, Saveetha Nagar, Chennai Bengaluru, NH 48, Chennai 602105, India. ramaiyan.dr@gmail.com
Received: May 29, 2024
Revised: July 26, 2024
Accepted: August 1, 2024
Published online: November 6, 2024
Processing time: 104 Days and 23.4 Hours
Core Tip

Core Tip: In this editorial, we provide a commentary on a case report. The authors aimed to study the rearranged during transfection (RET) gene mutations, clinical characteristics, and treatment strategies in a family with multiple endocrine neoplasia type 2 (MEN2). Although RET gene mutation increases the risk of endocrine tumors and hyperplasia, a lack of proper diagnosis and molecular testing can undermine the management of patients with MEN2. In this editorial article, we focus on the significance of molecular testing in MEN2.