Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 26, 2024; 12(3): 575-581
Published online Jan 26, 2024. doi: 10.12998/wjcc.v12.i3.575
Inetetamab combined with pyrotinib and chemotherapy in the treatment of breast cancer brain metastasis: A case report
Qing-Qing Dou, Ting-Ting Sun, Guo-Qiang Wang, Wei-Bing Tong
Qing-Qing Dou, Ting-Ting Sun, Guo-Qiang Wang, Graduate Student Institute, Inner Mongolia Medical University, Hohhot 010000, Inner Mongolia Autonomous Region, China
Wei-Bing Tong, Central Breast Area B, Beijing University Cancer Hospital Inner Mongolia Hospital, Hohhot 010000, Inner Mongolia Autonomous Region, China
Author contributions: Dou QQ is the main contributor of this case, mainly responsible for case information collection; Sun TT and Wang GQ have the same contribution to the paper, mainly responsible for picture collection and content verification; Dou QQ integrated the content and wrote the manuscript; Tong WB was mainly responsible for the review and evaluation of the manuscript; all authors have commented on the previous version of the manuscript and approve the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and all accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei-Bing Tong, MD, Chief Physician, Surgeon, Central Breast Area B, Beijing University Cancer Hospital Inner Mongolia Hospital, No. 42 Zhaowuda Road, Saihan District, Hohhot 010000, Inner Mongolia Autonomous Region, China. tongwei365@qq.com
Received: October 26, 2023
Peer-review started: October 26, 2023
First decision: November 8, 2023
Revised: November 21, 2023
Accepted: January 2, 2024
Article in press: January 2, 2024
Published online: January 26, 2024
Core Tip

Core Tip: Herein, we report the case of a patient with complex breast cancer brain metastasis. She underwent brain metastasis resection and received macromolecular mAbs, small molecule tyrosine kinase inhibitors, combination chemotherapeutic drugs, and radiation therapy. The overall condition of the patient was controlled and stabilized. We propose that combined macromolecule and small molecule chemotherapy and radiotherapy can provide a new option for the treatment of patients with breast cancer brain metastases. Magnetic resonance imaging of the brain of the patient showed that the tumor size was stable, and all the tumor indicators were within the normal range.